Second Leg of the 2025 Copa Sudamericana Semifinals: Lineups, Expectations, and Where to Watch!

Is playing the return leg at home after a draw away an advantage or added pressure? That’s the question running through the minds of many fans awaiting the second-leg matches of the 2025 Copa Sudamericana semifinals — and of those who enjoy Responsible Sports Betting!

Dreaming of becoming the greatest champion in the tournament’s history, Independiente del Valle conceded a stoppage-time equalizer to Atlético Mineiro. Now, Galo tries to take another step toward its first title at home. Meanwhile, Lanús had to recover after Universidad de Chile took a two-goal lead and now needs a simple win to advance.

To help you know what to expect, we’ve prepared this complete guide with possible lineups, absences, favorites, and of course, where to watch each match. Remember: the odds mentioned here are just indicators of favoritism — not guarantees of victory!

Atlético-MG vs Independiente del Valle

Last week, Atlético Mineiro and Independiente del Valle drew 1–1 in Quito — a heated match filled with controversy over refereeing decisions. Midfielder Junior Sornoza opened the scoring for the Ecuadorians with a penalty in the 11th minute, but attacking midfielder Dudu came off the bench to level the score at 91 minutes.

Both teams will face each other again this Tuesday, October 28, at 9:30 p.m., with the tie wide open. Whoever wins at the Arena MRV will advance to the final, while another draw will send the match to penalties.

Atlético-MG’s situation

Jorge Sampaoli has one confirmed absence for the decisive match in Belo Horizonte: midfielder Gustavo Scarpa is suspended due to yellow card accumulation. In addition, the Argentine coach won’t count on defender Lyanco, midfielder Patrick, and wingers Júnior Santos and Tomás Cuello — all sidelined with injuries.

Coming off a 1–0 win over Ceará in the Brazilian Championship, Atlético-MG rotated its squad but rested only a few players. Therefore, the probable lineup for Galo is:

Everson; Saravia, Vitor Hugo, Junior Alonso, and Guilherme Arana; Alan Franco, Fausto Vera (Alexsander), Igor Gomes, and Bernard; Dudu and Hulk (Rony).

Independiente del Valle’s situation

Javier Rabanal will have only one absence for the starting eleven: midfielder Ronald Briones, out with an injury since August. Meanwhile, defender Mateo Carabajal returns from suspension and is available to regain his spot in the lineup.

Independiente del Valle didn’t play over the weekend since their match against LDU was postponed. Therefore, the Ecuadorian league leaders come in more rested, likely fielding this formation:

Villar; Matías Fernández, Schunke, Carabajal, and Gustavo Cortez; Alcívar, Patrik Moreno, Guagua, and Sornoza; Spinelli and Hoyos.

Predictions

According to the betting odds, Atlético-MG is the favorite to win: 1.66 to win in regulation time, against 5.6 for Independiente del Valle and 3.6 for a draw. Considering qualification only, Galo remains favored with odds of 1.35 against 3.1 for Los Rayados del Valle.

Bet on Atlético-MG vs Independiente del Valle at Blaze!

Where to watch

Disney+ (Streaming)

Lanús vs Universidad de Chile

The Estadio Nacional de Chile saw another draw leave everything wide open. As visitors, Lanús started strong and had a dream first half with two goals from striker Rodrigo Castillo. However, Universidad de Chile fought back in the second half and equalized through Lucas Di Yorio and midfielder Charles Aránguiz, who made it 2–2 at the 99th minute.

This means that the match on Thursday, October 30, at 8 p.m., will grant a place in the final to whoever wins by any score. The Argentinians can take advantage of playing at home, though the Chileans may spring a surprise. One thing is certain: one of them will be fighting for their second Sudamericana title.

Lanús’s situation

Third in Group B of the Argentine Championship, Lanús has had a solid and competitive season. Since there was no domestic round due to the elections, the Granate will enter the field well-rested and ready to reach the final again.

Coach Mauricio Pellegrino will be without midfielders Raúl Loaiza and Felipe Peña Biafore and defender Ronaldo Dejesús — all recovering from injuries. The probable lineup for Lanús is:

Losada; Perez, Izquierdoz, Canales, and Marcich; Salvio, Medina, Cardozo, and Carrera; Moreno and Castillo.

Universidad de Chile’s situation

Far from the Chilean league title race, Universidad de Chile is focusing all its efforts on the Copa Sudamericana and fielded only three starters in last weekend’s match. The 1–0 loss to Universidad Católica left La U in fifth place, 20 points behind leaders Coquimbo Unido.

Gustavo Álvarez won’t have striker Rodrigo Contreras and midfielder Matías Sepúlveda, who suffered a muscle tear. To advance, the coach is expected to field:

Castellón; Hormazabal, Calderon, Zaldivia, and Ramírez (Fernández); Guerrero; Aránguiz, Poblete, and Altamirano; Assadi and Guerra.

Predictions

Playing at home and having a more consistent season, Lanús enters as the likely finalist. The 1.85 odds for a win in regulation time are more favorable than 3.4 for a draw and 4.4 for a Universidad de Chile victory. Regarding qualification, Lanús is priced at 1.45 to advance versus 2.66 for La U.

Where to Watch

Paramount+ (Streaming)

Bet on Lanús vs Universidad de Chile at Blaze!

Bet on the 2025 Copa Sudamericana at Blaze

Santa Cruz de la Sierra will no longer host the 2025 Copa Sudamericana Final, as CONMEBOL moved the match scheduled for November 22 to Defensores del Chaco Stadium in Asunción. We’re getting closer to finding out who will advance after such evenly matched duels, but one thing is certain: you can place your bets responsibly and worry-free, as Ordinance MESP 125/2024 authorizes betting on the tournament!

Before planning your betting experience, remember the importance of studying data, statistics, and market rules — for more tips, visit our Sports Betting Encyclopedia. Understand that betting is not an investment or a source of income, but a form of entertainment.

Never use money outside your financial reality or that you might need for essentials. Betting is an exciting hobby full of risks, and doing it without awareness can seriously impact your finances and mental health — and even lead to addiction.

Ready to feel the thrill as the ball rolls? Bet on the 2025 Copa Sudamericana at Blaze and play responsibly!